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pentobarbital will decrease the extent or effect of netupitant/palonosetron by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Netupitant is especially metabolized by CYP3A4; avoid use in individuals who're chronically applying a solid CYP3A4 inducerYou'll want to see your healthcare provider as recomme

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